The Wine Route is superb, but use the trains when possible, walk, or take a river boat – just don’t risk drink driving if you are sampling the goodies along the way. In Germany the European blood alcohol limit of 0.5 mg per ml stands, unless you are involved in an accident, in which case it drops to 0.3mg. If you're in a fatal accident in Germany and over the limit, you could serve five years. So, best rule of thumb: don’t drink at all when driving.
Several parts of the Eifel National Park are completely closed to the public due to the fact that there are still some WW2 minefields. There is no device available to detect them at present, and so always obey the signs, and stay away from mines.
On some one way streets, cyclists are allowed to travel in both directions, so keep an eye out.
Always wear your helmet cycling.
Take care driving on the motorways, as Germans do like to put the foot down, and flash their lights if you are not going fast enough. Don’t feel under pressure to do a Top Gear.